It is known that prenatal care is important for the health of both the mother and her baby. Now, more research are looking at the relationship between a poor maternal diet and the development of disease later in life.
Researchers funded by the Biotechnology and Biological Sciences Research
Council showed that, in both rats and humans, individuals who
experience a poor diet in the womb are less able to store fats correctly later in life.
Mechanism: In general, excess calories are stored in fat cells. When these cells become unable to absorb the excess, fat will be deposited in places like the liver which can lead to type II diabetes. This process is controlled by a molecule called miR-483-3p. The researchers found that miR-483-3p was produced at higher levels in individuals who had experienced a poor diet in their mother's wombs than those who were better nourished. As a result, cells that are exposed to high levels of this molecule have a reduced ability to form fat cells and to store fats, leading to insulin resistance and higher risk of type II diabetes.
For reference click here
Researchers funded by the Biotechnology and Biological Sciences Research
Council showed that, in both rats and humans, individuals who
experience a poor diet in the womb are less able to store fats correctly later in life. Mechanism: In general, excess calories are stored in fat cells. When these cells become unable to absorb the excess, fat will be deposited in places like the liver which can lead to type II diabetes. This process is controlled by a molecule called miR-483-3p. The researchers found that miR-483-3p was produced at higher levels in individuals who had experienced a poor diet in their mother's wombs than those who were better nourished. As a result, cells that are exposed to high levels of this molecule have a reduced ability to form fat cells and to store fats, leading to insulin resistance and higher risk of type II diabetes.
For reference click here
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